Pharmaceutical Grade Ethyl Oleate Safe Organic Solvents Cas
111-62-6 for Injectable
Chemical Name:Ethyl Oleate
Other name: 9-Octadecenoic acid (Z)-, ethyl ester; Ethyl oleate,
mixture of isomers; ; ethyl octadec-9-enoate; ethyl
(9Z)-octadec-9-enoate; ethyl (9E)-octadec-9-enoate
Molecular Formula: C20H38O2
Formula Weight: 310.51
CAS No. 111-62-6
Ethyl oleate is a fatty acid ester formed by the condensation of
oleic acid and ethanol. It is a colorless to light yellow liquid.
Ethyl oleate is produced by the body during ethanol intoxication.
Ethyl oleate is one of the fatty acid ethyl esters (FAEE) that is
formed in the body after ingestion of ethanol. There is a growing
body of research literature that implicates FAEEs such as ethyl
oleate as the toxic mediators of ethanol in the body (pancreas,
liver, heart, and brain). Among the speculations is that ethyl
oleate may be the toxic mediator of alcohol infetal alcohol
syndrome. The oral ingestion of ethyl oleate has been carefully
studied and due to rapid degradation in the digestive tract it
appears safe for oral ingestion. Ethyl oleate is not currently
approved by the U.S. Food and Drug Administration for any
injectable use. However, it is used by compounding pharmacies as a
vehicle for intramuscular drug delivery, in some cases to prepare
the daily doses of progesterone in support of pregnancy. Studies
which document the safe use of ethyl oleate in pregnancy for both
the mother and the fetus have never been performed.
Ethyl oleate is used as a solvent for pharmaceutical drug
preparations involving lipophilic substances such as steroids. It
also finds use as a lubricant and a plasticizer.
Ethyl oleate is regulated as a food additive by the Food and Drug
Administration under "Food Additives Permitted for Direct Addition
to Food for Human Consumption".
(Z)-9-Octadecenoic acid ethyl
Biochemistry;Fatty Acid Esters (Plasticizer);Functional
Materials;Higher Fatty Acids & Higher
Alcohols;Plasticizer;Unsaturated Higher Fatty Acid Esters;Fatty
Acid Derivatives & Lipids;Glycerols
216-218 °C15 mm Hg
0.87 g/mL at 25 °C(lit.)
CAS DataBase Reference
111-62-6(CAS DataBase Reference)
NIST Chemistry Reference
9-Octadecenoic acid (Z)-, ethyl ester(111-62-6)
EPA Substance Registry System
9-Octadecenoic acid (9Z)-, ethyl ester(111-62-6)
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